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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT3
All Species:
20.91
Human Site:
S65
Identified Species:
38.33
UniProt:
O60678
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60678
NP_005779.1
531
59903
S65
T
S
A
E
E
T
F
S
H
C
K
S
E
H
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092890
531
59784
S65
T
S
A
E
E
T
F
S
H
C
K
S
E
H
Q
Dog
Lupus familis
XP_534089
541
60618
S75
I
S
A
E
E
T
F
S
H
C
K
S
E
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q922H1
532
59884
S63
A
S
A
E
E
T
F
S
H
C
K
L
E
H
Q
Rat
Rattus norvegicus
O70467
528
59401
S63
R
S
A
E
E
T
F
S
H
C
K
L
E
H
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505718
571
63850
S105
T
S
A
E
E
T
F
S
H
C
T
S
E
H
Q
Chicken
Gallus gallus
XP_420907
526
59430
C63
C
S
P
E
D
V
F
C
H
C
N
A
E
H
Q
Frog
Xenopus laevis
Q8AV13
369
42306
Zebra Danio
Brachydanio rerio
Q5RGQ2
419
48204
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396035
525
60169
D64
L
V
A
S
H
R
F
D
L
K
N
F
I
I
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192186
519
58632
N66
C
R
E
S
H
S
F
N
L
V
Q
I
S
T
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82210
366
41153
Baker's Yeast
Sacchar. cerevisiae
P38074
348
39768
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.1
90.9
N.A.
89.8
89.2
N.A.
78.8
70.8
35.4
35.7
N.A.
N.A.
42.5
N.A.
45
Protein Similarity:
100
N.A.
96.8
95.1
N.A.
93.9
93.9
N.A.
85.9
83.2
49.1
52.3
N.A.
N.A.
62.5
N.A.
63.6
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
86.6
N.A.
93.3
53.3
0
0
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
86.6
86.6
N.A.
93.3
66.6
0
0
N.A.
N.A.
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.1
31.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
54
0
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
16
0
0
0
0
0
0
8
0
54
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
54
47
0
0
0
0
0
0
0
54
0
0
% E
% Phe:
0
0
0
0
0
0
70
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
16
0
0
0
54
0
0
0
0
54
8
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
39
0
0
0
8
% K
% Leu:
8
0
0
0
0
0
0
0
16
0
0
16
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
16
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
54
% Q
% Arg:
8
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
54
0
16
0
8
0
47
0
0
0
31
8
0
0
% S
% Thr:
24
0
0
0
0
47
0
0
0
0
8
0
0
8
0
% T
% Val:
0
8
0
0
0
8
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _